Prognostic Model in Patients with Early-stage Squamous Cell Carcinoma of the Uterine Cervix

Pathologic examination of specimens from radical surgery in patients with early-stage cervical cancers provides information that has predictive prognostic potential. Several pathologic features have been extensively studied and recognized as standard prognostic features such as extent of tumor invasion, presence of lymphovascular space invasion (LVSI), parametrial involvement, and lymph node metastasis (Biewenga et al., 2009; 2011; Suprasert et al., 2010). The pathologic characteristics at the invasive margin (tumor front) were found to provide prognostic information in several types of cancers, including the uterine cervix (Bryne et al., 1998; Kristensen et al., 1999; Horn et al., 2006a; Eggen et al., 2007). The major characteristics of invasive